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Corestem Inc neuronata r
Neuronata R, supplied by Corestem Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/neuronata-r/neuronata+r/pmc13176351-21-2-3
Average 86 stars, based on 1 article reviews
neuronata r - by Bioz Stars, 2026-10
86/100 stars

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Related Articles

In Vitro:

Article Title: Mesenchymal and induced pluripotent stem cell–based therapeutics: a comparison
Article Snippet: Corestem, Inc. , NeuroNata-R ® , Autologous hBM-MSCs , Amyotrophic lateral sclerosis , Approved , South Korea.

Article Title: Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options
Article Snippet: Neuronata-R , BM-MSC , Corestem , ALS (Lou Gehrig’s Disease) , South Korea MFDS, 2014.

Article Title: Stem cell therapies in the clinic
Article Snippet: NeuroNata‐R® (Corestem) is approved for amyotrophic lateral sclerosis (ALS), and Stemirac (Nipro) for spinal cord injury.

Article Title: Cellular expansion of MSCs : Shifting the regenerative potential
Article Snippet: Neuronata‐R , Corestem Inc. , Amyotrophic lateral sclerosis , South Korea (2014) , Human BM‐MSC , Autologous , 1 m cells/kg (every 2 weeks).

Article Title: Developing standards to support the clinical translation of stem cells.
Article Snippet: The guidelines recommend that research related to human embryos (eg, preimplantation stages of human development, in vitro human embryo culture, derivation of TABLE 1 Representative approved stem cell products on the market Region Trade name Cell type Manufacturer Indications United States ALLOCORD HPC cord blood SSM Cardinal Glennon Children's Medical Center Hematopoietic and immunologic reconstitution United States Ducord HPC cord blood Duke University School of Medicine Hematopoietic and immunologic reconstitution United States Clevecord HPC cord blood Cleveland Cord Blood Center Hematopoietic and immunologic reconstitution United States Hemacord HPC cord blood New York Blood Center, Inc Hematopoietic and immunologic reconstitution Europe Alofisel Allogeneic MSC extracted from adipose tissue Takeda Complex anal fistulas in adults with Crohn's disease Europe Zynteglo Genetically modified autologous CD34+ cell enriched population that contains HSC Bluebird bio (Netherlands) B.V. Beta-thalassemia Europe Strimvelis Autologous CD34+ enriched cell fraction contains genetically modified CD34+ cells Orchard Therapeutics (Netherlands) BV Severe combined immunodeficiency Japan Temcell Allogeneic MSC from BM JCR Pharmaceuticals Co. Ltd Acute GVHD Japan Stemirac Autologous MSC from BM Nipro Corporation Spinal cord injury South Korea NeuroNATA-R Autologous MSC from BM CORESTEM ALS South Korea Cupistem Autologous adipose-derived MSC Anterogen Crohn's disease complicated with anal fistul South Korea Cartistem Allogeneic derived MSC from UCB Medipost Damaged cartilage South Korea Hearticellgram-AMI Autologous MSC from BM Pharmicell Aute myocardial infarction Canada/New Zealand Prochymal (Remestemcel-L) Human MSC Osiris Acute GVHD in pediatric patients Australia MPC Mesenchymal precursor cell Mesoblast Repair and regeneration of damaged tissue India Stempeucel Autologous MSC from BM Stempeutics CLI Abbreviations: ALS, amyotrophic lateral sclerosis; BM, bone marrow; CLI, critical limb ischemia; GVHD, graft-vs-host disease; HPC, hematopoietic progenitor cell; HSC, hematopoietic stem cells; MSC, mesenchymal stem cells; UCB, umbilical cord blood. nloaded from https://stem cellsjournals.onlinelibrary.w iley.com /doi/10.1002/sct3.13035 by < Shibboleth> -m em ber@ bcu.ac.uk, W iley O nline L ibrary on [01/05/2024].

Article Title: Exploring the Immunomodulatory Aspect of Mesenchymal Stem Cells for Treatment of Severe Coronavirus Disease 19
Article Snippet: In line with this, there has been global approval of several MSC-based therapies, including Temcell HS Inj (JCR Pharmaceuticals, approved in Japan, 2015) for GvHD; Cellgram-AMI (FCB-Pharmicell, approved in South Korea, 2011) for myocardial infarction; Prochymal/remestemcel-L (Osiris, approved in Canada and New Zealand, 2012) for GvHD; Cartistem (Medipost, approved in South Korea, 2012) for knee articular cartilage defect; Neuronata-R (Corestem Inc., approved in South Korea, 2014) for amyotrophic lateral sclerosis; and Alofisel (TiGenix NV/Takeda, approved in Europe, 2018) for complex perianal fistulas in CD, among others [ ] ( https://alliancerm.org/available-products/ , accessed on 25 May 2022).

Embryo Culture:

Article Title: Mesenchymal and induced pluripotent stem cell–based therapeutics: a comparison
Article Snippet: Corestem, Inc. , NeuroNata-R ® , Autologous hBM-MSCs , Amyotrophic lateral sclerosis , Approved , South Korea.

Article Title: Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options
Article Snippet: Neuronata-R , BM-MSC , Corestem , ALS (Lou Gehrig’s Disease) , South Korea MFDS, 2014.

Article Title: Stem cell therapies in the clinic
Article Snippet: NeuroNata‐R® (Corestem) is approved for amyotrophic lateral sclerosis (ALS), and Stemirac (Nipro) for spinal cord injury.

Article Title: Cellular expansion of MSCs : Shifting the regenerative potential
Article Snippet: Neuronata‐R , Corestem Inc. , Amyotrophic lateral sclerosis , South Korea (2014) , Human BM‐MSC , Autologous , 1 m cells/kg (every 2 weeks).

Article Title: Developing standards to support the clinical translation of stem cells.
Article Snippet: The guidelines recommend that research related to human embryos (eg, preimplantation stages of human development, in vitro human embryo culture, derivation of TABLE 1 Representative approved stem cell products on the market Region Trade name Cell type Manufacturer Indications United States ALLOCORD HPC cord blood SSM Cardinal Glennon Children's Medical Center Hematopoietic and immunologic reconstitution United States Ducord HPC cord blood Duke University School of Medicine Hematopoietic and immunologic reconstitution United States Clevecord HPC cord blood Cleveland Cord Blood Center Hematopoietic and immunologic reconstitution United States Hemacord HPC cord blood New York Blood Center, Inc Hematopoietic and immunologic reconstitution Europe Alofisel Allogeneic MSC extracted from adipose tissue Takeda Complex anal fistulas in adults with Crohn's disease Europe Zynteglo Genetically modified autologous CD34+ cell enriched population that contains HSC Bluebird bio (Netherlands) B.V. Beta-thalassemia Europe Strimvelis Autologous CD34+ enriched cell fraction contains genetically modified CD34+ cells Orchard Therapeutics (Netherlands) BV Severe combined immunodeficiency Japan Temcell Allogeneic MSC from BM JCR Pharmaceuticals Co. Ltd Acute GVHD Japan Stemirac Autologous MSC from BM Nipro Corporation Spinal cord injury South Korea NeuroNATA-R Autologous MSC from BM CORESTEM ALS South Korea Cupistem Autologous adipose-derived MSC Anterogen Crohn's disease complicated with anal fistul South Korea Cartistem Allogeneic derived MSC from UCB Medipost Damaged cartilage South Korea Hearticellgram-AMI Autologous MSC from BM Pharmicell Aute myocardial infarction Canada/New Zealand Prochymal (Remestemcel-L) Human MSC Osiris Acute GVHD in pediatric patients Australia MPC Mesenchymal precursor cell Mesoblast Repair and regeneration of damaged tissue India Stempeucel Autologous MSC from BM Stempeutics CLI Abbreviations: ALS, amyotrophic lateral sclerosis; BM, bone marrow; CLI, critical limb ischemia; GVHD, graft-vs-host disease; HPC, hematopoietic progenitor cell; HSC, hematopoietic stem cells; MSC, mesenchymal stem cells; UCB, umbilical cord blood. nloaded from https://stem cellsjournals.onlinelibrary.w iley.com /doi/10.1002/sct3.13035 by < Shibboleth> -m em ber@ bcu.ac.uk, W iley O nline L ibrary on [01/05/2024].

Article Title: Exploring the Immunomodulatory Aspect of Mesenchymal Stem Cells for Treatment of Severe Coronavirus Disease 19
Article Snippet: In line with this, there has been global approval of several MSC-based therapies, including Temcell HS Inj (JCR Pharmaceuticals, approved in Japan, 2015) for GvHD; Cellgram-AMI (FCB-Pharmicell, approved in South Korea, 2011) for myocardial infarction; Prochymal/remestemcel-L (Osiris, approved in Canada and New Zealand, 2012) for GvHD; Cartistem (Medipost, approved in South Korea, 2012) for knee articular cartilage defect; Neuronata-R (Corestem Inc., approved in South Korea, 2014) for amyotrophic lateral sclerosis; and Alofisel (TiGenix NV/Takeda, approved in Europe, 2018) for complex perianal fistulas in CD, among others [ ] ( https://alliancerm.org/available-products/ , accessed on 25 May 2022).

Genetically Modified:

Article Title: Mesenchymal and induced pluripotent stem cell–based therapeutics: a comparison
Article Snippet: Corestem, Inc. , NeuroNata-R ® , Autologous hBM-MSCs , Amyotrophic lateral sclerosis , Approved , South Korea.

Article Title: Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options
Article Snippet: Neuronata-R , BM-MSC , Corestem , ALS (Lou Gehrig’s Disease) , South Korea MFDS, 2014.

Article Title: Stem cell therapies in the clinic
Article Snippet: NeuroNata‐R® (Corestem) is approved for amyotrophic lateral sclerosis (ALS), and Stemirac (Nipro) for spinal cord injury.

Article Title: Cellular expansion of MSCs : Shifting the regenerative potential
Article Snippet: Neuronata‐R , Corestem Inc. , Amyotrophic lateral sclerosis , South Korea (2014) , Human BM‐MSC , Autologous , 1 m cells/kg (every 2 weeks).

Article Title: Developing standards to support the clinical translation of stem cells.
Article Snippet: The guidelines recommend that research related to human embryos (eg, preimplantation stages of human development, in vitro human embryo culture, derivation of TABLE 1 Representative approved stem cell products on the market Region Trade name Cell type Manufacturer Indications United States ALLOCORD HPC cord blood SSM Cardinal Glennon Children's Medical Center Hematopoietic and immunologic reconstitution United States Ducord HPC cord blood Duke University School of Medicine Hematopoietic and immunologic reconstitution United States Clevecord HPC cord blood Cleveland Cord Blood Center Hematopoietic and immunologic reconstitution United States Hemacord HPC cord blood New York Blood Center, Inc Hematopoietic and immunologic reconstitution Europe Alofisel Allogeneic MSC extracted from adipose tissue Takeda Complex anal fistulas in adults with Crohn's disease Europe Zynteglo Genetically modified autologous CD34+ cell enriched population that contains HSC Bluebird bio (Netherlands) B.V. Beta-thalassemia Europe Strimvelis Autologous CD34+ enriched cell fraction contains genetically modified CD34+ cells Orchard Therapeutics (Netherlands) BV Severe combined immunodeficiency Japan Temcell Allogeneic MSC from BM JCR Pharmaceuticals Co. Ltd Acute GVHD Japan Stemirac Autologous MSC from BM Nipro Corporation Spinal cord injury South Korea NeuroNATA-R Autologous MSC from BM CORESTEM ALS South Korea Cupistem Autologous adipose-derived MSC Anterogen Crohn's disease complicated with anal fistul South Korea Cartistem Allogeneic derived MSC from UCB Medipost Damaged cartilage South Korea Hearticellgram-AMI Autologous MSC from BM Pharmicell Aute myocardial infarction Canada/New Zealand Prochymal (Remestemcel-L) Human MSC Osiris Acute GVHD in pediatric patients Australia MPC Mesenchymal precursor cell Mesoblast Repair and regeneration of damaged tissue India Stempeucel Autologous MSC from BM Stempeutics CLI Abbreviations: ALS, amyotrophic lateral sclerosis; BM, bone marrow; CLI, critical limb ischemia; GVHD, graft-vs-host disease; HPC, hematopoietic progenitor cell; HSC, hematopoietic stem cells; MSC, mesenchymal stem cells; UCB, umbilical cord blood. nloaded from https://stem cellsjournals.onlinelibrary.w iley.com /doi/10.1002/sct3.13035 by < Shibboleth> -m em ber@ bcu.ac.uk, W iley O nline L ibrary on [01/05/2024].

Article Title: Exploring the Immunomodulatory Aspect of Mesenchymal Stem Cells for Treatment of Severe Coronavirus Disease 19
Article Snippet: In line with this, there has been global approval of several MSC-based therapies, including Temcell HS Inj (JCR Pharmaceuticals, approved in Japan, 2015) for GvHD; Cellgram-AMI (FCB-Pharmicell, approved in South Korea, 2011) for myocardial infarction; Prochymal/remestemcel-L (Osiris, approved in Canada and New Zealand, 2012) for GvHD; Cartistem (Medipost, approved in South Korea, 2012) for knee articular cartilage defect; Neuronata-R (Corestem Inc., approved in South Korea, 2014) for amyotrophic lateral sclerosis; and Alofisel (TiGenix NV/Takeda, approved in Europe, 2018) for complex perianal fistulas in CD, among others [ ] ( https://alliancerm.org/available-products/ , accessed on 25 May 2022).

Derivative Assay:

Article Title: Mesenchymal and induced pluripotent stem cell–based therapeutics: a comparison
Article Snippet: Corestem, Inc. , NeuroNata-R ® , Autologous hBM-MSCs , Amyotrophic lateral sclerosis , Approved , South Korea.

Article Title: Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options
Article Snippet: Neuronata-R , BM-MSC , Corestem , ALS (Lou Gehrig’s Disease) , South Korea MFDS, 2014.

Article Title: Stem cell therapies in the clinic
Article Snippet: NeuroNata‐R® (Corestem) is approved for amyotrophic lateral sclerosis (ALS), and Stemirac (Nipro) for spinal cord injury.

Article Title: Cellular expansion of MSCs : Shifting the regenerative potential
Article Snippet: Neuronata‐R , Corestem Inc. , Amyotrophic lateral sclerosis , South Korea (2014) , Human BM‐MSC , Autologous , 1 m cells/kg (every 2 weeks).

Article Title: Developing standards to support the clinical translation of stem cells.
Article Snippet: The guidelines recommend that research related to human embryos (eg, preimplantation stages of human development, in vitro human embryo culture, derivation of TABLE 1 Representative approved stem cell products on the market Region Trade name Cell type Manufacturer Indications United States ALLOCORD HPC cord blood SSM Cardinal Glennon Children's Medical Center Hematopoietic and immunologic reconstitution United States Ducord HPC cord blood Duke University School of Medicine Hematopoietic and immunologic reconstitution United States Clevecord HPC cord blood Cleveland Cord Blood Center Hematopoietic and immunologic reconstitution United States Hemacord HPC cord blood New York Blood Center, Inc Hematopoietic and immunologic reconstitution Europe Alofisel Allogeneic MSC extracted from adipose tissue Takeda Complex anal fistulas in adults with Crohn's disease Europe Zynteglo Genetically modified autologous CD34+ cell enriched population that contains HSC Bluebird bio (Netherlands) B.V. Beta-thalassemia Europe Strimvelis Autologous CD34+ enriched cell fraction contains genetically modified CD34+ cells Orchard Therapeutics (Netherlands) BV Severe combined immunodeficiency Japan Temcell Allogeneic MSC from BM JCR Pharmaceuticals Co. Ltd Acute GVHD Japan Stemirac Autologous MSC from BM Nipro Corporation Spinal cord injury South Korea NeuroNATA-R Autologous MSC from BM CORESTEM ALS South Korea Cupistem Autologous adipose-derived MSC Anterogen Crohn's disease complicated with anal fistul South Korea Cartistem Allogeneic derived MSC from UCB Medipost Damaged cartilage South Korea Hearticellgram-AMI Autologous MSC from BM Pharmicell Aute myocardial infarction Canada/New Zealand Prochymal (Remestemcel-L) Human MSC Osiris Acute GVHD in pediatric patients Australia MPC Mesenchymal precursor cell Mesoblast Repair and regeneration of damaged tissue India Stempeucel Autologous MSC from BM Stempeutics CLI Abbreviations: ALS, amyotrophic lateral sclerosis; BM, bone marrow; CLI, critical limb ischemia; GVHD, graft-vs-host disease; HPC, hematopoietic progenitor cell; HSC, hematopoietic stem cells; MSC, mesenchymal stem cells; UCB, umbilical cord blood. nloaded from https://stem cellsjournals.onlinelibrary.w iley.com /doi/10.1002/sct3.13035 by < Shibboleth> -m em ber@ bcu.ac.uk, W iley O nline L ibrary on [01/05/2024].

Article Title: Exploring the Immunomodulatory Aspect of Mesenchymal Stem Cells for Treatment of Severe Coronavirus Disease 19
Article Snippet: In line with this, there has been global approval of several MSC-based therapies, including Temcell HS Inj (JCR Pharmaceuticals, approved in Japan, 2015) for GvHD; Cellgram-AMI (FCB-Pharmicell, approved in South Korea, 2011) for myocardial infarction; Prochymal/remestemcel-L (Osiris, approved in Canada and New Zealand, 2012) for GvHD; Cartistem (Medipost, approved in South Korea, 2012) for knee articular cartilage defect; Neuronata-R (Corestem Inc., approved in South Korea, 2014) for amyotrophic lateral sclerosis; and Alofisel (TiGenix NV/Takeda, approved in Europe, 2018) for complex perianal fistulas in CD, among others [ ] ( https://alliancerm.org/available-products/ , accessed on 25 May 2022).



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Image Search Results


Summary of major MSC clinical trials for ALS.

Journal: Stem Cells Translational Medicine

Article Title: Optimal Therapeutic Strategy of Bone Marrow-Originated Autologous Mesenchymal Stromal/Stem Cells for ALS

doi: 10.1093/stcltm/szad095

Figure Lengend Snippet: Summary of major MSC clinical trials for ALS.

Article Snippet: NCT01363401 , Korea/Corestem , Phase I , Two injections with a 26-day interval ( n = 7) , Autologous BM-MSCs (Lenzumestrocel, Neuronata-R® Inj) , Intrathecal , Safe , Oh et al. .

Techniques: Clinical Proteomics, Injection, Control

Summary of major MSC clinical trials for ALS.

Journal: Stem Cells Translational Medicine

Article Title: Optimal Therapeutic Strategy of Bone Marrow-Originated Autologous Mesenchymal Stromal/Stem Cells for ALS

doi: 10.1093/stcltm/szad095

Figure Lengend Snippet: Summary of major MSC clinical trials for ALS.

Article Snippet: NCT01363401 , Korea/Corestem , Phase II, RCT without a sham procedure , Randomized (1:1) (i) Two injections with a 26-day interval ( n = 32) (ii) Control group ( n = 27) , Autologous BM-MSCs (Lenzumestrocel, Neuronata-R® Inj) , Intrathecal , Safe; positive clinical effect, reduced pro-inflammatory cytokines , Oh et al. .

Techniques: Clinical Proteomics, Injection, Control

Clinical trials listed on clinicaltrials.gov for amyotrophic lateral sclerosis

Journal: Stem Cells Translational Medicine

Article Title: Neural Cells for Neurodegenerative Diseases in Clinical Trials

doi: 10.1093/stcltm/szad041

Figure Lengend Snippet: Clinical trials listed on clinicaltrials.gov for amyotrophic lateral sclerosis

Article Snippet: 13 , ALS , Corestem , Autologous BM MSC [Lenzumestrocel (Neuronata-R Inj.)] , IT , 2 M/kg or 5 M/kg , 115 , 2021 , 3 , NCT04745299.

Techniques: Clinical Proteomics, Expressing, Transplantation Assay, Injection